NSAIDs

NSAIDs (non-steroidal anti-inflammatory drugs) are medicines that reduce pain, swelling, and stiffness caused by inflammation.

In Sri Lanka, the common NSAIDs used are:

  • Celecoxib (Zycel)
  • Aceclofenac (Zerodol)
  • Naproxen
  • Ibuprofen
  • Meloxicam
  • Diclofenac sodium (Voltaren)
  • Diclofenac potassium (Cataflam)

They are especially helpful in conditions like rheumatoid arthritis, psoriatic arthritis, osteoarthritis, and ankylosing spondylitis.

How Do NSAIDs Work?

In arthritis, inflammation in the joints causes pain, stiffness, and swelling. NSAIDs block chemicals (prostaglandins) that cause inflammation, giving quick relief.

They help with symptoms but do not cure arthritis or stop long-term joint damage.

Benefits of NSAIDs
  • Fast relief from joint pain and stiffness.
  • May take 2–4 weeks of regular use for full benefit.
  • Allow patients to move more freely and maintain daily activities.
How to Take NSAIDs Safely
  • Always take exactly as prescribed by your doctor.
  • Avoid overuse: do not take more tablets than prescribed or for longer than prescribed.
  • To reduce stomach irritation, your doctor may also prescribe a proton pump inhibitor such as Omeprazole or Esomeprazole.
  • Take with or after food to reduce stomach upset.
Safety Points
  • If you experience severe stomach pain or develop black stools, stop immediately and seek medical help.
  • If you have a history of stomach ulcers, kidney disease, or heart disease, it is best to avoid NSAIDs. Speak to your doctor before taking them.
  • Rarely, NSAIDs can cause allergic reactions such as skin rashes or swelling. If this happens, stop the medicine and contact your doctor.
Key Reminders
  1. NSAIDs relieve symptoms but do not stop disease progression.
  2. Best results may take 2–4 weeks of continuous use.
  3. Use only as prescribed—avoid overuse.
  4. Use stomach protection (Omeprazole/Esomeprazole) if advised.
  5. Stop and seek medical help if severe stomach pain or black stools occur.
  6. Tell your doctor about any history of ulcers, kidney disease, or heart disease before use.
Further Reference

Adapted from the Australian Rheumatology Association (ARA) Patient Information on NSAIDs: